![]() Artificial fibre-base filter for removing erythrocytes from blood and method of removing erythrocyte
专利摘要:
The invention relates to medical chemistry, a filter and a method for removing red blood cells from the blood. The purpose of the invention is to increase the degree of red blood cell removal. For this, a filter is used as follows. Blood is applied to the upper side of layer 1 of man-made fibers, fixed with mesh 5. Red blood cells and white blood cells are separated in the layer from the plasma passing through layer 4 and entering the reaction layer 2 or collection. Plasma collection is stopped when the maximum flowing volume reaches 50% of the adsorption layer, after which the layer of artificial fibers together with the grid 5 is separated by means of the fixed part 4a of the grid. The reaction layer is ready for further work with it. Glass fibers, with a diameter of 0.2-2.5 µm and packing density of 0.1-0.5 g / cm, are used as artificial fibers. 2 sec. f-ly, 1 ill. ABOUT) 公开号:SU1424723A3 申请号:SU813315700 申请日:1981-08-04 公开日:1988-09-15 发明作者:Фогель Петер;Браун Ханс-Петер;Бергер Дитер;Вернер ВОЛЬФГАНГ 申请人:Берингер Маннхайм Гмбх (Фирма); IPC主号:
专利说明:
one ( four 0 i ( 0 x sn The invention relates to medicine, in particular to the field of medical chemistry and concerns a filter and a method for removing red blood cells from the blood. The aim of the invention is to increase the degree of red blood cell removal, The drawing shows a filter for implementing a method for removing red blood cells from blood. Layer 1 of man-made fibers, which used glass fiber with an average diameter of 0.2 to 2.5 μm and a packing density of 0.1 to 0.5 g / cm, is placed on top of the reaction layer 2 located on a rigid base 3 , and separated from the layer 2 by a thin form-resistant and liquid-permeable layer 4, which is a net of woven or piled plastic threads. The loose portion of this mesh 4a is intended to remove layers 1 and 4 after the separation of red blood cells and white blood cells from blood. Layer 1 is also fixed over the top of grid 3. The reaction layer 2 can be made in the form of a suction carrier or porous polymer film. The base 3 can be made of a thicker polymer film, rigid cardboard, glass, etc. The filter works as follows Blood is applied to the upper side of layer 1, fixed with a mesh 5. Red blood cells, as well as white blood cells, are separated in layer 1 from the plasma that passes through layer 4 and enters the reaction layer 2 or collection. Plasma collection is stopped after the maximum outflow volume reaches 50% of the adsorption layer, after which layer 1 is separated with mesh 5 by means of the loose part of mesh 4a. Reaction layer 2 is ready for further work with it. A filter for removing erythrocytes from the blood, characterized by scrubbed glass fiber diameter and packing density, makes it possible to increase the degree of separation of erythrocytes from plasma and virtually eliminate the passage of red blood cells through the filtering layer.
权利要求:
Claims (2) [1] 1. Filter for removing red blood cells from blood based on artificial fibers, characterized in that, in order to improve the degree of red blood cell removal, glass fibers with an average diameter of 0.2-2.5 µm and a packing density of 0.1 are used as artificial fibers - 0.5 g / cm. [2] 2. A method for removing red blood cells from the blood by passing it through a layer of artificial fibers, characterized in that, in order to increase the degree of red blood cell removal, the transmission is stopped after reaching the maximum flowing volume of 50% of the adsorption layer. Compiled by O. Kabanov Editor A.Dolinich Tehred M.Hodanich Proofreader S.Shekmar Order 4700/58 Circulation 655 VNIIPI USSR State Committee for inventions and discoveries 113035, Moscow, Zh-35, Raushsk nab., 4/5 Subscription
类似技术:
公开号 | 公开日 | 专利标题 SU1424723A3|1988-09-15|Artificial fibre-base filter for removing erythrocytes from blood and method of removing erythrocytes from blood JP2523938B2|1996-08-14|Platelet purification filter US4330410A|1982-05-18|Separation of leukocytes from leukocyte-containing suspension by filtration US4923620A|1990-05-08|Device for depletion of the leukocyte content of blood and blood components US4925572A|1990-05-15|Device and method for depletion of the leukocyte content of blood and blood components US5258127A|1993-11-02|Leucocyte depleting filter device and method of use US5855782A|1999-01-05|Arrangement for removing substances from liquids, in particular blood EP0267286B1|1993-05-26|Filter medium for selectively removing leucocytes CA1102710A|1981-06-09|Membrane unit and device for cleansing blood US5498336A|1996-03-12|Leukocyte-removing filter and leukocyte-removing apparatus furnished therewith EP0683687B1|2003-07-09|Leukocyte removal method and use of a filter unit for same US4976861A|1990-12-11|Method for determining the wetting characteristic of a porous medium EP0313348A2|1989-04-26|Device and method for depletion of the leukocyte content of blood and blood components JPH09196911A|1997-07-31|Blood filter unit KR920703170A|1992-12-17|Blood transfusion apparatus and method for human transfusion CN1073614A|1993-06-30|Method and apparatus from the biological fluid separated plasma JPS56110625A|1981-09-01|Separating method of blood plasma and apparatus for the same JPH0316651A|1991-01-24|Total blood analyzing element US4609461A|1986-09-02|Apparatus for purifying blood US6063282A|2000-05-16|Simultaneous filtration of numerous samples using microfibers US20010000204A1|2001-04-12|Method for removing tumor cells from tumor cell-contaminated stem cell products JPH11237378A|1999-08-31|Method for separating serum from whole blood US4944884A|1990-07-31|Body fluid purification method using activated carbon fibers of novoloid resin origin JPH04187206A|1992-07-03|Leucocyte separator and production of leucocyte separating material US6328167B1|2001-12-11|Blood filter cartridge
同族专利:
公开号 | 公开日 DE3172720D1|1985-11-28| FI812419L|1982-02-06| AT16218T|1985-11-15| US4477575B1|1992-04-21| JPH0664054B2|1994-08-22| DK155636B|1989-05-01| PL141490B1|1987-07-31| EP0045476B1|1985-10-23| DK155636C|1989-09-25| US4477575A|1984-10-16| HU186398B|1985-07-29| CA1177374A|1984-11-06| AU7364481A|1982-02-11| EP0045476A1|1982-02-10| ES8205558A1|1982-08-16| AU525394B2|1982-11-04| IE811779L|1982-02-05| DE3029579A1|1982-02-18| DK345381A|1982-02-06| FI71999C|1987-03-09| JPH0854387A|1996-02-27| JPS5753661A|1982-03-30| IL63492D0|1981-11-30| ZA815337B|1982-08-25| IE51623B1|1987-01-21| DD201388A5|1983-07-20| IL63492A|1984-04-30| CS235005B2|1985-04-16| PL232469A1|1982-04-26| JP2680799B2|1997-11-19| ES504542A0|1982-08-16| FI71999B|1986-11-28| DE3029579C2|1985-12-12|
引用文献:
公开号 | 申请日 | 公开日 | 申请人 | 专利标题 US3092465A|1960-03-25|1963-06-04|Miles Lab|Diagnostic test device for blood sugar| US3448041A|1965-06-14|1969-06-03|Roy L Swank|Method and apparatus for treating blood preliminary to its use in transfusions| US3552925A|1967-07-13|1971-01-05|Miles Lab|Whole blood separation method and test using same| US3552928A|1967-07-19|1971-01-05|Miles Lab|Whole blood separation means and test system using same| US3663374A|1970-08-14|1972-05-16|Geomet|Method and apparatus for quantitating enzyme activity| US3791933A|1971-02-25|1974-02-12|Geomet|Rapid methods for assay of enzyme substrates and metabolites| DE2118455B1|1971-04-16|1972-09-21|Boehringer Mannheim Gmbh|Test strips| DE2222951C3|1972-05-10|1975-03-06|Geomet, Inc., Rockville, Md. |Device for determining the enzyme activity in whole blood| DE2356353C2|1973-11-12|1975-07-17|B. Braun Melsungen Ag, 3508 Melsungen|Device for filtering blood| CA1056282A|1974-03-25|1979-06-12|Charles T. Goodhue|Multilayer analytical elements for use in the assay of cholesterol| US3983005A|1974-03-25|1976-09-28|Eastman Kodak Company|Integral element for the analysis of cholesterol| CA1041903A|1974-11-07|1978-11-07|Corning Glass Works|Blood coagulation and separation| US4189382A|1974-11-07|1980-02-19|Sherwood Medical Industries Inc.|Blood coagulation and separation| DE2453813A1|1974-11-13|1976-05-26|Greiner & Soehne C A|Test tube for blood specimens - quartz wadding or granules used as coagulating substance| US4012325A|1975-01-08|1977-03-15|Eastman Kodak Company|Biological fluid dispenser and separator| JPS5328495A|1976-08-27|1978-03-16|Ajinomoto Kk|Coagulation accelarating process| CA1095819A|1977-01-14|1981-02-17|Eastman Kodak Company|Element for analysis of liquids| US4069017A|1977-01-14|1978-01-17|Eastman Kodak Company|Colorimetric assay for bilirubin| GB2018151B|1978-03-06|1982-12-08|Asahi Chemical Ind|Seperation of leukocytes from leukocyte-containing suspension by filtration| US4246107A|1978-03-06|1981-01-20|Asahi Kasei Kogyo Kabushiki Kaisha|Separation of lymphocytes from lymphocyte-containing suspension by filtration| DE2821469A1|1978-05-17|1979-11-22|Boehringer Mannheim Gmbh|DIAGNOSTIC AGENT FOR DETERMINING UREA| JPS587332Y2|1978-06-06|1983-02-08| FR2430784A1|1978-07-11|1980-02-08|Domnick Hunter Eng|Filter for submicron particles in pressure systems - has element formed from microfibres of borosilicate glass supported in housing either side| JPS6151737B2|1978-08-31|1986-11-10|Fuji Photo Film Co Ltd| US4256696A|1980-01-21|1981-03-17|Baxter Travenol Laboratories, Inc.|Cuvette rotor assembly|DK157218C|1981-07-06|1990-04-23|Per Stahl Skov|PROCEDURE FOR DETERMINING OR DETERMINING HISTAMINE IN BODY LIQUIDS, SPECIFIC BLOOD OR BLOOD FRACTIONS, AND ANALYTICAL DEVICE FOR APPLICATION BY PURPOSE OF THE PROCEDURE| DE3130749C2|1981-08-04|1984-06-07|Boehringer Mannheim Gmbh, 6800 Mannheim|Rapid diagnostic agent and method for its use, in particular for quantitative determinations| EP0160640A1|1982-12-22|1985-11-13|University Of Queensland|Microassay of cell adherence| DE3247608A1|1982-12-23|1984-07-05|Boehringer Mannheim Gmbh, 6800 Mannheim|TEST STRIP| DE3302383C2|1983-01-25|1985-08-29|Michael J. 8000 München Lysaght|Method and device for obtaining blood plasma| DE3323973A1|1983-07-02|1985-01-03|Boehringer Mannheim Gmbh, 6800 Mannheim|ERYTHROCYTE RETENTION SUBSTRATES| USRE34405E|1983-08-01|1993-10-12|Abbott Laboratories|Determination of analytes in particle-containing medium| EP0155003B1|1984-03-15|1990-07-04|ASAHI MEDICAL Co., Ltd.|Filtering unit for removing leukocytes| EP0160916B1|1984-04-27|1991-07-10|Fuji Photo Film Co., Ltd.|Part of an analytical element for the analysis of a solid in a liquid sample| DE3425118A1|1984-07-07|1986-01-16|Boehringer Mannheim Gmbh, 6800 Mannheim|NEW REDOX INDICATORS| DE3441149A1|1984-11-10|1986-05-15|Merck Patent Gmbh, 6100 Darmstadt|METHOD FOR SEVERAL BLOOD SEPARATION| DE3508427A1|1985-03-09|1986-09-11|Merck Patent Gmbh, 6100 Darmstadt|AGENT AND METHOD FOR SEPARATING PLASMA OR SERUM FROM WHOLE BLOOD| US4678757A|1985-04-11|1987-07-07|Smithkline Diagnostics, Inc.|Device and method for whole blood separation and analysis| CA1262432A|1985-04-22|1989-10-24|M. Sultan Siddiqi|Sealed reagent matrix| US4623461A|1985-05-31|1986-11-18|Murex Corporation|Transverse flow diagnostic device| DE3523439A1|1985-06-29|1987-01-08|Boehringer Mannheim Gmbh|TEST CARRIER| DE3523969A1|1985-07-04|1987-01-08|Boehringer Mannheim Gmbh|Coagulation-neutral, hydrophilic glass fibers| TW203120B|1985-10-04|1993-04-01|Abbott Lab| US4839296A|1985-10-18|1989-06-13|Chem-Elec, Inc.|Blood plasma test method| US5160701A|1986-02-18|1992-11-03|Abbott Laboratories|Solid-phase analytical device and method for using same| US5081017A|1986-02-18|1992-01-14|Texas Bioresource Corporation|Method and apparatus for detection and quantitation of bacteria| US4916056A|1986-02-18|1990-04-10|Abbott Laboratories|Solid-phase analytical device and method for using same| US4906439A|1986-03-25|1990-03-06|Pb Diagnostic Systems, Inc.|Biological diagnostic device and method of use| DE3610429A1|1986-03-27|1987-10-01|Boehringer Mannheim Gmbh|Coagulation-neutral, hydrophilic glass fibers| DE3616496A1|1986-05-16|1987-11-19|Boehringer Mannheim Gmbh|ANALYZING ELEMENT FOR DETERMINING COAGLING PARAMETERS| US4935346A|1986-08-13|1990-06-19|Lifescan, Inc.|Minimum procedure system for the determination of analytes| DE3630999A1|1986-09-12|1988-03-17|Boehringer Mannheim Gmbh|MULTI-LAYER TEST CARRIER| US5057438A|1986-09-24|1991-10-15|Agency Of Industrial Science And Technology|Electrophoretic antigen-antibody determination with laminate of multiple membranes| US4753776A|1986-10-29|1988-06-28|Biotrack, Inc.|Blood separation device comprising a filter and a capillary flow pathway exiting the filter| DE3638654A1|1986-11-12|1988-05-26|Boehringer Mannheim Gmbh|TEST CARRIER FOR ANALYTICAL DETERMINATION OF A COMPONENT OF A BODY LIQUID| US4849340A|1987-04-03|1989-07-18|Cardiovascular Diagnostics, Inc.|Reaction system element and method for performing prothrombin time assay| US4959324A|1989-03-16|1990-09-25|Chemtrak, Inc.|Sample pad assay initiation device and method of making| US5423989A|1988-05-19|1995-06-13|Chemtrack, Inc.|Plasma forming device| US4987085A|1987-06-22|1991-01-22|Chemtrak Inc.|Blood filtering metering device| DE3721236A1|1987-06-27|1989-01-05|Boehringer Mannheim Gmbh|METHOD FOR PRODUCING A DIAGNOSTIC TEST CARRIER AND CORRESPONDING TEST CARRIER| US4883764A|1987-07-20|1989-11-28|Kloepfer Mary A|Blood test strip| DE3725766A1|1987-08-04|1989-02-16|Boehringer Mannheim Gmbh|TEST CARRIER FOR DETERMINING AN ANALYTE FROM BLOOD AND METHOD FOR THE PRODUCTION THEREOF| DE3729001A1|1987-08-31|1989-03-09|Behringwerke Ag|DEVICE AND METHOD FOR SEPARATING BLOOD CELLS FROM BODY LIQUIDS CONTAINING ERYTHROCYTES AND THE USE THEREOF| DE3733084A1|1987-09-30|1989-04-13|Boehringer Mannheim Gmbh|TEST CARRIER FOR ANALYTICAL DETERMINATION OF A COMPONENT OF A BODY LIQUID| US4923620A|1987-10-20|1990-05-08|Pall Corporation|Device for depletion of the leukocyte content of blood and blood components| US4925572A|1987-10-20|1990-05-15|Pall Corporation|Device and method for depletion of the leukocyte content of blood and blood components| US4880548A|1988-02-17|1989-11-14|Pall Corporation|Device and method for separating leucocytes from platelet concentrate| NL8800796A|1988-03-29|1989-10-16|X Flow Bv|METHOD FOR THE CHEMICAL ANALYSIS OF BODY FLUID COMPONENTS, AND A TESTING DEVICE AND TEST PACKAGE FOR SUCH ANALYSIS.| US4994238A|1988-06-09|1991-02-19|Daffern George M|Constant volume chemical analysis test device| AU2684488A|1988-06-27|1990-01-04|Carter-Wallace, Inc.|Test device and method for colored particle immunoassay| US5208147A|1988-07-21|1993-05-04|Radiometer A/S|Means for measuring a characteristic in a sample fluid| US5096809A|1988-07-25|1992-03-17|Pacific Biotech, Inc.|Whole blood assays using porous membrane support devices| DE3826057A1|1988-07-30|1990-02-01|Boehringer Mannheim Gmbh|TEST TESTER FOR THE ANALYTICAL DETERMINATION OF AN INGREDIENT OF A LIQUID SAMPLE| US5338513A|1988-07-30|1994-08-16|Boehringer Mannheim Gmbh|Test carrier for the analytical determination of a component of a liquid sample| US5171688A|1988-08-30|1992-12-15|Cholestech Corporation|Self-corrected assay device| US4946603A|1988-11-17|1990-08-07|Crystal Diagnostics, Inc.|Electronegatively charged blood filter and blood cell separation method| JPH0721455B2|1988-12-01|1995-03-08|株式会社京都第一科学|Tools and Methods for Analyzing Specific Components in Liquid Samples| DE3844104A1|1988-12-28|1990-07-05|Boehringer Mannheim Gmbh|TEST CARRIER ANALYSIS SYSTEM| US5202268A|1988-12-30|1993-04-13|Environmental Diagnostics, Inc.|Multi-layered test card for the determination of substances in liquids| DE3903114A1|1989-02-02|1990-08-09|Boehringer Mannheim Gmbh|METHOD FOR DETERMINING AN ENZYME FROM AN ISOZYME MIXTURE, AND TEST CARRIER SUITABLE FOR THIS, AND USE THEREOF| US4948561A|1989-02-09|1990-08-14|Eastman Kodak Company|Multiple level filter device and kit containing same| US5114350A|1989-03-08|1992-05-19|Cholestech Corporation|Controlled-volume assay apparatus| US5156954A|1989-03-08|1992-10-20|Cholestech Corporation|Assay device and method using a signal-modulating compound| US5064541A|1989-04-07|1991-11-12|Abbott Laboratories|Devices and methods for the collection of a predetermined volume of plasma or serum| US4933092A|1989-04-07|1990-06-12|Abbott Laboratories|Methods and devices for the separation of plasma or serum from whole blood| US5344561A|1989-05-09|1994-09-06|Pall Corporation|Device for depletion of the leucocyte content of blood and blood components| US5229012A|1989-05-09|1993-07-20|Pall Corporation|Method for depletion of the leucocyte content of blood and blood components| US5087556A|1989-05-17|1992-02-11|Actimed Laboratories, Inc.|Method for quantitative analysis of body fluid constituents| US5234813A|1989-05-17|1993-08-10|Actimed Laboratories, Inc.|Method and device for metering of fluid samples and detection of analytes therein| US5009780A|1989-07-20|1991-04-23|Millipore Corporation|Multi-well filtration apparatus| DE3929032C2|1989-09-01|1998-09-03|Boehringer Mannheim Gmbh|Method for the determination of HDL cholesterol by means of a rapid diagnostic with integrated fractionation step| USRE39915E1|1989-09-01|2007-11-06|Roche Diagnostics Gmbh|Method for the determination of HDL cholesterol by means of a rapid diagnostic agent with an integrated fractionating step| US5360545A|1989-09-12|1994-11-01|Pall Corporation|Filter for obtaining platelets| US5258126A|1989-09-12|1993-11-02|Pall Corporation|Method for obtaining platelets| US5075078A|1989-10-05|1991-12-24|Abbott Laboratories|Self-performing immunochromatographic device| EP0423784B1|1989-10-18|1997-01-02|Fuji Photo Film Co., Ltd.|Dry analysis element for quantitative analysis of analyte contained in whole blood| US5622870A|1989-11-27|1997-04-22|Behringwerke Ag|Device and method for completing a fluidic circuit| US5435970A|1989-12-18|1995-07-25|Environmental Diagnostics, Inc.|Device for analysis for constituents in biological fluids| US5266219A|1989-12-28|1993-11-30|Pall Corporation|Device and method for separating plasma from blood| CA2031975A1|1990-01-12|1991-07-13|Brian R. Barkes|Device and method of separating and assaying whole blood| DE4001155A1|1990-01-17|1991-07-18|Boehringer Mannheim Gmbh|DIAGNOSTIC AGENT FOR DETECTING CHOLESTERIN| US5110724A|1990-04-02|1992-05-05|Cholestech Corporation|Multi-analyte assay device| DE4015589A1|1990-05-15|1991-11-21|Boehringer Mannheim Gmbh|DEVICE AND THE USE THEREOF FOR SEPARATING PLASMA FROM WHOLE BLOOD| US5302299A|1990-05-24|1994-04-12|Pall Corporation|Biological semi-fluid processing assembly| US5213964A|1990-07-16|1993-05-25|Cholestech Corporation|High-density lipoprotein solid-base precipitation assay method| US5213965A|1990-07-16|1993-05-25|Cholestech Corporation|Solid-phase precipitation assay device| US5147606A|1990-08-06|1992-09-15|Miles Inc.|Self-metering fluid analysis device| US5118428A|1990-11-13|1992-06-02|Quidel|Method to remove red blood cells from whole blood samples| US5139685A|1991-03-26|1992-08-18|Gds Technology, Inc.|Blood separation filter assembly and method| US5468648A|1991-05-29|1995-11-21|Smithkline Diagnostics, Inc.|Interrupted-flow assay device| US5877028A|1991-05-29|1999-03-02|Smithkline Diagnostics, Inc.|Immunochromatographic assay device| US6168956B1|1991-05-29|2001-01-02|Beckman Coulter, Inc.|Multiple component chromatographic assay device| US5607863A|1991-05-29|1997-03-04|Smithkline Diagnostics, Inc.|Barrier-controlled assay device| US5998220A|1991-05-29|1999-12-07|Beckman Coulter, Inc.|Opposable-element assay devices, kits, and methods employing them| US5869345A|1991-05-29|1999-02-09|Smithkline Diagnostics, Inc.|Opposable-element assay device employing conductive barrier| US5186843A|1991-07-22|1993-02-16|Ahlstrom Filtration, Inc.|Blood separation media and method for separating plasma from whole blood| GR1001410B|1991-08-02|1993-11-30|Ortho Pharma Corp|Device and method for conducting biological assays containing particulate screening system.| DE69220871T2|1991-10-03|1997-11-20|Bayer Ag|Device and method for the separation and analysis of whole blood| JPH05188053A|1992-01-10|1993-07-27|Sanwa Kagaku Kenkyusho Co Ltd|Instrument for separating serum or plasma component from blood| DE69329377T2|1992-03-10|2001-04-05|Quidel Corp|RELEASE AGENT FOR RED BLOOD CELLS IN EXAMINATIONS WITH SPECIFIC BINDING| JP2903273B2|1992-04-20|1999-06-07|富士写真フイルム株式会社|Method for transporting dry analytical film pieces and cartridge| DE4217474A1|1992-05-27|1993-12-02|Boehringer Mannheim Gmbh|Method and means for determining an analyte| DE4217732A1|1992-05-29|1993-12-02|Boehringer Mannheim Gmbh|Test carrier containing fleece layer| US5427739A|1992-08-27|1995-06-27|Schering-Plough Healthcare Products, Inc.|Apparatus for performing immunoassays| US5460974A|1992-10-13|1995-10-24|Miles Inc.|Method of assaying whole blood for HDL cholesterol| US5766552A|1993-04-20|1998-06-16|Actimed Laboratories, Inc.|Apparatus for red blood cell separation| DE69432840T2|1993-04-20|2004-05-13|Fuji Photo Film Co., Ltd., Minami-Ashigara|Dry analytical film chip| US5416026A|1993-10-04|1995-05-16|I-Stat Corporation|Method for detecting the change in an analyte due to hemolysis in a fluid sample| US5536472A|1993-11-22|1996-07-16|Fuji Photo Film Co., Ltd.|Chemical analysis element cartridge| JP3318115B2|1994-07-05|2002-08-26|富士写真フイルム株式会社|Dry analytical film supply device| EP0772484B1|1994-07-28|2008-02-27|Pall Corporation|Fibrous web and process of preparing same| US5582907A|1994-07-28|1996-12-10|Pall Corporation|Melt-blown fibrous web| CA2156226C|1994-08-25|1999-02-23|Takayuki Taguchi|Biological fluid analyzing device and method| US5597532A|1994-10-20|1997-01-28|Connolly; James|Apparatus for determining substances contained in a body fluid| US5589399A|1994-10-21|1996-12-31|First Medical, Inc.|System and method for plasma separation and measurement| US5916521A|1995-01-04|1999-06-29|Spectral Diagnostics, Inc.|Lateral flow filter devices for separation of body fluids from particulate materials| WO1996024425A1|1995-02-09|1996-08-15|First Medical, Inc.|Peristaltic system and method for plasma separation| US5725774A|1995-04-07|1998-03-10|Lxn Corp.|Whole blood separation method and devices using the same| US6319676B1|1995-05-02|2001-11-20|Carter Wallace, Inc.|Diagnostic detection device and method| WO1996035952A1|1995-05-09|1996-11-14|Smithkline Diagnostics, Inc.|Devices and methods for separating cellular components of blood from liquid portion of blood| US5755231A|1995-05-17|1998-05-26|Plus Bio, Inc.|Test strip including integral specimen flow retarding structure| US6241886B1|1995-06-09|2001-06-05|Toyo Boseki Kabushiki Kaisha|Plasma separation filter| DE19523049A1|1995-06-24|1997-01-02|Boehringer Mannheim Gmbh|Multilayer analysis element for the determination of an analyte in a liquid| US7635597B2|1995-08-09|2009-12-22|Bayer Healthcare Llc|Dry reagent particle assay and device having multiple test zones and method therefor| CA2203759A1|1995-08-28|1997-03-06|Ryusuke Okamoto|Serum or plasma separating compositions| US5981294A|1995-11-29|1999-11-09|Metrika, Inc.|Device for blood separation in a diagnostic device| US5753497A|1995-12-22|1998-05-19|Universal Health Watch Inc|Diagnostic assay providing blood separation| DE19605582A1|1996-02-15|1997-08-21|Bayer Ag|Graphite nonwovens as functional layers in diagnostic test kits| US5962215A|1996-04-05|1999-10-05|Mercury Diagnostics, Inc.|Methods for testing the concentration of an analyte in a body fluid| US5821073A|1996-05-09|1998-10-13|Syntron Bioresearch, Inc.|Method and apparatus for single step assays of whole blood| AUPO087196A0|1996-07-05|1996-08-01|Belclan Pty. Limited|Blood separation module| DE19629656A1|1996-07-23|1998-01-29|Boehringer Mannheim Gmbh|Diagnostic test carrier with multilayer test field and method for the determination of analyte with its aid| DE19629654A1|1996-07-23|1998-05-07|Boehringer Mannheim Gmbh|Diagnostic test carrier with capillary gap| DE19629657A1|1996-07-23|1998-01-29|Boehringer Mannheim Gmbh|Volume-independent diagnostic test carrier and method for determining analyte with its aid| US6391265B1|1996-08-26|2002-05-21|Biosite Diagnostics, Inc.|Devices incorporating filters for filtering fluid samples| WO1998010283A1|1996-09-05|1998-03-12|Srl, Inc.|Sample protective container integral with body fluid separating sheet| US5968765A|1996-11-08|1999-10-19|Mercury Diagnostics, Inc.|Opaque reaction matrix for the analysis of the whole blood| US5879951A|1997-01-29|1999-03-09|Smithkline Diagnostics, Inc.|Opposable-element assay device employing unidirectional flow| JP3487396B2|1997-01-31|2004-01-19|松下電器産業株式会社|Biosensor and manufacturing method thereof| US5939252A|1997-05-09|1999-08-17|Lennon; Donald J.|Detachable-element assay device| US5948695A|1997-06-17|1999-09-07|Mercury Diagnostics, Inc.|Device for determination of an analyte in a body fluid| JP3903098B2|1997-07-18|2007-04-11|富士フイルム株式会社|Blood filtration method| DE19753847A1|1997-12-04|1999-06-10|Roche Diagnostics Gmbh|Analytical test element with capillary channel| DE19753849A1|1997-12-04|1999-06-10|Roche Diagnostics Gmbh|Analytical test element with a tapered capillary channel| US7494816B2|1997-12-22|2009-02-24|Roche Diagnostic Operations, Inc.|System and method for determining a temperature during analyte measurement| US7390667B2|1997-12-22|2008-06-24|Roche Diagnostics Operations, Inc.|System and method for analyte measurement using AC phase angle measurements| AU738325B2|1997-12-22|2001-09-13|Roche Diagnostics Operations Inc.|Meter| US7407811B2|1997-12-22|2008-08-05|Roche Diagnostics Operations, Inc.|System and method for analyte measurement using AC excitation| US8148164B2|2003-06-20|2012-04-03|Roche Diagnostics Operations, Inc.|System and method for determining the concentration of an analyte in a sample fluid| US8071384B2|1997-12-22|2011-12-06|Roche Diagnostics Operations, Inc.|Control and calibration solutions and methods for their use| DE19816550A1|1997-12-24|1999-06-24|Roche Diagnostics Gmbh|Universally applicable structure of an analysis element and its use for analyte determination| US6673629B2|1998-01-15|2004-01-06|Abbott Laboratories|Neutralization of polycations in a chromatographic device for whole blood use| JPH11237378A|1998-02-19|1999-08-31|Fuji Photo Film Co Ltd|Method for separating serum from whole blood| US6471868B1|1998-04-10|2002-10-29|Fuji Photo Film Co., Ltd.|Method of preparing glass fiber filter| US6106732A|1998-04-16|2000-08-22|Binax Services, Inc.|Integral blood plasma or serum isolation, metering and transport device| US6908770B1|1998-07-16|2005-06-21|Board Of Regents, The University Of Texas System|Fluid based analysis of multiple analytes by a sensor array| US6214629B1|1998-08-06|2001-04-10|Spectral Diagnostics, Inc.|Analytical test device and method for use in medical diagnoses| US6410341B1|1998-08-06|2002-06-25|Spectral Diagnostics, Inc.|Analytical test device and method for use in medical diagnoses| US6171870B1|1998-08-06|2001-01-09|Spectral Diagnostics, Inc.|Analytical test device and method for use in medical diagnoses| CN1250970C|1998-08-06|2006-04-12|光谱诊断公司|Analytical test device and method| CA2254223A1|1998-11-16|2000-05-16|Biophys, Inc.|Device and method for analyzing a biologic sample| DE19912365A1|1999-03-19|2000-09-21|Roche Diagnostics Gmbh|Multi-layer analytical tool| US7192729B2|1999-07-06|2007-03-20|General Atomics|Methods for assaying homocysteine| US6376210B1|1999-07-06|2002-04-23|General Atomics|Methods and compositions for assaying analytes| DE60031988T2|1999-07-16|2007-06-14|The Board Of Regents Of The University Of Texas System, Austin|METHOD AND DEVICE FOR DELIVERING SAMPLE TO A CHEMICAL SENSOR MATRIX| US7022517B1|1999-07-16|2006-04-04|Board Of Regents, The University Of Texas System|Method and apparatus for the delivery of samples to a chemical sensor array| DE19945828B4|1999-09-24|2011-06-01|Roche Diagnostics Gmbh|Analysis element and method for the determination of an analyte in liquid| US6696240B1|1999-10-26|2004-02-24|Micronix, Inc.|Capillary test strip to separate particulates| US6458326B1|1999-11-24|2002-10-01|Home Diagnostics, Inc.|Protective test strip platform| US6627057B1|1999-12-23|2003-09-30|Roche Diagnostic Corporation|Microsphere containing sensor| DE60043049D1|1999-12-28|2009-11-12|Arkray Inc|Blood test device| AU3320001A|2000-01-31|2001-08-07|Univ Texas|Portable sensor array system| AU2767901A|2000-02-25|2001-09-03|Gen Atomics|Mutant nucleic binding enzymes and use thereof in diagnostic, detection and purification methods| US6610504B1|2000-04-10|2003-08-26|General Atomics|Methods of determining SAM-dependent methyltransferase activity using a mutant SAH hydrolase| JP3655283B2|2000-06-01|2005-06-02|松下電器産業株式会社|Biosensor and blood component analysis method| JP3543000B2|2000-06-28|2004-07-14|松下電器産業株式会社|Biosensor| JP4184073B2|2000-07-31|2008-11-19|松下電器産業株式会社|Biosensor| US6776888B2|2000-07-31|2004-08-17|Matsushita Electric Industrial Co., Ltd.|Biosensor| DE10046173C2|2000-09-08|2003-04-03|Inst Chemo Biosensorik|Device and method for separating undissolved components from biological liquids| US6852874B2|2000-10-02|2005-02-08|The Scripps Research Institute|Second cycle asymmetric dihydroxylation reaction| US6645359B1|2000-10-06|2003-11-11|Roche Diagnostics Corporation|Biosensor| US6814843B1|2000-11-01|2004-11-09|Roche Diagnostics Corporation|Biosensor| JP4183902B2|2000-12-27|2008-11-19|松下電器産業株式会社|Biosensor| US7195923B2|2001-01-31|2007-03-27|Scripps Laboratories, Inc.|Ratiometric determination of glycated protein| US6525330B2|2001-02-28|2003-02-25|Home Diagnostics, Inc.|Method of strip insertion detection| US6562625B2|2001-02-28|2003-05-13|Home Diagnostics, Inc.|Distinguishing test types through spectral analysis| US6541266B2|2001-02-28|2003-04-01|Home Diagnostics, Inc.|Method for determining concentration of an analyte in a test strip| US6869405B2|2001-03-30|2005-03-22|Becton, Dickinson And Company|Blunt cannula and filter assembly and method of use with point-of-care testing cartridge| WO2002084291A1|2001-04-12|2002-10-24|Arkray, Inc.|Specimen analyzing implement| WO2002100278A1|2001-06-08|2002-12-19|Roche Diagnostics Gmbh|Sampling devices and methods utilizing a horizontal capillary test strip| DE10150549A1|2001-10-12|2003-04-17|Roche Diagnostics Gmbh|Separation module, useful for the separation of corpuscles from blood, comprises two channels from a junction with a faster flow in one channel taking most of the particles, and a slower flow with few particles through the other channel| US7018843B2|2001-11-07|2006-03-28|Roche Diagnostics Operations, Inc.|Instrument| JPWO2003042680A1|2001-11-14|2005-03-10|松下電器産業株式会社|Biosensor| EP1495335A2|2001-12-21|2005-01-12|Polymer Technology Systems, Inc.|Test strip and method for determining hdl cholesterol concentration from whole blood or plasma| DE60207196T2|2002-04-09|2006-07-20|Cholestech Corp., Hayward|Method and apparatus for quantification of high density lipoprotein cholesterol| AU2003228711C1|2002-04-26|2010-01-07|Board Of Regents, The University Of Texas System|Method and system for the detection of cardiac risk factors| DE10252223A1|2002-11-11|2004-05-27|Roche Diagnostics Gmbh|Device for separating and dispensing plasma| DE50309809D1|2002-11-16|2008-06-19|Dade Behring Marburg Gmbh|SCD40L, PAPP-A AND PLACENTAL GROWTH FACTORAS BIOCHEMICAL MARKER COMBINATIONS IN CARDIOVASCULAR DISEASES| US20060228256A1|2003-02-07|2006-10-12|Board Of Regents, The University Of Texas System|Multi-shell microspheres with integrated chomatographic and detection layers for use in array sensors| US7228973B2|2003-05-23|2007-06-12|Ahlstrom Mt. Holly Springs, Llc|Nonwoven fibrous media especially useful for the separation of blood constituents| US7645373B2|2003-06-20|2010-01-12|Roche Diagnostic Operations, Inc.|System and method for coding information on a biosensor test strip| US8058077B2|2003-06-20|2011-11-15|Roche Diagnostics Operations, Inc.|Method for coding information on a biosensor test strip| US7718439B2|2003-06-20|2010-05-18|Roche Diagnostics Operations, Inc.|System and method for coding information on a biosensor test strip| US7645421B2|2003-06-20|2010-01-12|Roche Diagnostics Operations, Inc.|System and method for coding information on a biosensor test strip| US7604721B2|2003-06-20|2009-10-20|Roche Diagnostics Operations, Inc.|System and method for coding information on a biosensor test strip| US8206565B2|2003-06-20|2012-06-26|Roche Diagnostics Operation, Inc.|System and method for coding information on a biosensor test strip| US7452457B2|2003-06-20|2008-11-18|Roche Diagnostics Operations, Inc.|System and method for analyte measurement using dose sufficiency electrodes| US7597793B2|2003-06-20|2009-10-06|Roche Operations Ltd.|System and method for analyte measurement employing maximum dosing time delay| US7488601B2|2003-06-20|2009-02-10|Roche Diagnostic Operations, Inc.|System and method for determining an abused sensor during analyte measurement| WO2005012557A1|2003-08-04|2005-02-10|Sanwa Kagaku Kenkyusho Co., Ltd.|Method of collecting erythrocytes and method of assaying sorbitol| DE10346417A1|2003-10-07|2005-06-02|Roche Diagnostics Gmbh|Analytical test element comprising a network for forming a capillary channel| DE10350880A1|2003-10-31|2005-06-02|Roche Diagnostics Gmbh|Method for determining an analyte by means of an extraction layer| DE10356752A1|2003-12-04|2005-06-30|Roche Diagnostics Gmbh|Coated test elements| US7150995B2|2004-01-16|2006-12-19|Metrika, Inc.|Methods and systems for point of care bodily fluid analysis| US8465696B2|2004-02-03|2013-06-18|Polymer Technology Systems, Inc.|Dry test strip with controlled flow and method of manufacturing same| US7625721B2|2004-02-03|2009-12-01|Polymer Technology Systems, Inc.|Non-precipitating bodily fluid analysis system| US20060062688A1|2004-02-03|2006-03-23|Polymer Technology Systems, Inc.|Bodily fluid analysis system| US7435577B2|2004-02-03|2008-10-14|Polymer Technology Systems, Inc.|Direct measurement of chlolesterol from low density lipoprotein with test strip| RU2006132051A|2004-02-06|2008-03-20|БАЙЕР ХЕЛТКЭР ЭлЭлСи |OXIDIZABLE COMPOUNDS AS AN INTERNAL STANDARD FOR BIOSENSORS AND METHOD OF APPLICATION| US8105849B2|2004-02-27|2012-01-31|Board Of Regents, The University Of Texas System|Integration of fluids and reagents into self-contained cartridges containing sensor elements| US8101431B2|2004-02-27|2012-01-24|Board Of Regents, The University Of Texas System|Integration of fluids and reagents into self-contained cartridges containing sensor elements and reagent delivery systems| WO2005090969A1|2004-03-18|2005-09-29|Fuji Photo Film Co., Ltd.|Analysis element for use in method of testing specimen| US7867780B2|2004-03-30|2011-01-11|Whatman, Inc.|Lateral flow format, materials and methods| US7384760B2|2004-04-30|2008-06-10|General Atomics|Methods for assaying inhibitors of S-adenosylhomocysteinehydrolase and S-adenosylmethionine -dependent methyltransferase| US7569126B2|2004-06-18|2009-08-04|Roche Diagnostics Operations, Inc.|System and method for quality assurance of a biosensor test strip| US7556723B2|2004-06-18|2009-07-07|Roche Diagnostics Operations, Inc.|Electrode design for biosensor| EP1793906B1|2004-08-05|2015-01-28|Akers Biosciences, Inc.|Blood separator and method of separating a fluid fraction from whole blood| US20060062690A1|2004-08-17|2006-03-23|Polymer Technology Systems, Inc.|Apparatus and method of manufacturing bodily fluid test strip| US20060040258A1|2004-08-23|2006-02-23|Huiyan Guo|Water-soluble conjugates and methods of preparation| DE102004051847B4|2004-10-25|2008-09-18|Dade Behring Marburg Gmbh|Ratio of PIGF and Flt-1 as a prognostic parameter in cardiovascular diseases| DE102004058794A1|2004-12-07|2006-06-08|Roche Diagnostics Gmbh|Process for coating membranes| US20060205090A1|2005-03-14|2006-09-14|Newton Michael W|Water-soluble conjugates for electrochemical detection| GB0509919D0|2005-05-16|2005-06-22|Ralph Ellerker 1795 Ltd|Improvements to door closure system| GB2426334A|2005-05-20|2006-11-22|Orion Diagnostica Oy|Application of a reagent to a matrix material| CA2608162C|2005-05-23|2013-11-12|Phadia Ab|Two step lateral flow assay methods and devices| EP1910824A4|2005-05-31|2012-11-21|Labnow Inc|Methods and compositions related to determination and use of white blood cell counts| RU2441238C2|2005-07-20|2012-01-27|БАЙЕР ХЕЛТКЭА ЭлЭлСи|Strobed amperometry| KR20130100022A|2005-09-30|2013-09-06|바이엘 헬스케어 엘엘씨|Gated voltammetry analyte determination| WO2008086019A1|2007-01-09|2008-07-17|Cholestech Corporation|Device and method for measuring ldl-associated cholesterol| NL1033365C2|2007-02-09|2008-08-12|Medavinci Dev B V|Device and method for separating and analyzing blood.| CN103157400B|2007-06-21|2014-12-24|简·探针公司|Instrument and method for exposing container to multiple areas| US20090078657A1|2007-09-26|2009-03-26|Honeywell International Inc.|Device for separation of particulates from a biological sample| US8535617B2|2007-11-30|2013-09-17|Kimberly-Clark Worldwide, Inc.|Blood cell barrier for a lateral flow device| US9968931B2|2007-12-12|2018-05-15|Nan Zhang|Rapid and efficient filtering whole blood in capillary flow device| US9482677B2|2008-02-27|2016-11-01|Scios Inc.|Method, composition and device for sampling natriuretic peptides in a biological fluid| JP5207290B2|2008-04-24|2013-06-12|国立大学法人北陸先端科学技術大学院大学|Method for producing chromatostrip and lateral flow type chromatostrip| NL2001577C2|2008-05-14|2009-11-17|Medavinci Dev B V|Device and method for separating and analyzing blood.| CA2725977A1|2008-05-27|2009-12-03|Zbx Corporation|Enzymatic analytical membrane, test device and method| JP5405916B2|2008-06-24|2014-02-05|パナソニック株式会社|Biosensor, method for manufacturing the same, and detection system including the same| EP2349566B1|2008-10-03|2016-01-06|Micronics, Inc.|Microfluidic apparatus and methods for performing blood typing and crossmatching| US20100093551A1|2008-10-09|2010-04-15|Decision Biomarkers, Inc.|Liquid Transfer and Filter System| BR112013002064B1|2010-07-27|2020-11-24|Northwestern University|DEVICE AND METHODS FOR BLOOD PLASMA FILTERING| US8956859B1|2010-08-13|2015-02-17|Aviex Technologies Llc|Compositions and methods for determining successful immunization by one or more vaccines| JP5902167B2|2010-08-20|2016-04-13|シトネット ゲーエムベーハー ウント ツェーオー.カーゲー|Method for isolating urea while removing hindering CO2| WO2012116308A1|2011-02-24|2012-08-30|Gen-Probe Incorporated|Systems and methods for distinguishing optical signals of different modulation frequencies in an optical signal detector| US20120282634A1|2011-04-22|2012-11-08|Polymer Technology Systems, Inc.|Blood separation system and method for a dry test strip| US9630374B2|2011-12-22|2017-04-25|Dsm Ip Assets B.V.|Multilayered woven manufacture and use of the multilayer woven manufacture as carriers for dried matrix spot applications| JP6489418B2|2012-01-24|2019-03-27|ミニケア ビー.ブイ.|Filter unit for cartridge| EP2845001B1|2012-05-03|2016-12-14|Qualigen, Inc.|Whole blood analytic device and method therefor| PL2676606T3|2012-06-20|2017-10-31|Fabpulous B V|Quick test device and method| KR101952957B1|2012-06-20|2019-02-28|주식회사 미코바이오메드|Sensor strip| US9427707B2|2012-08-10|2016-08-30|Jean I. Montagu|Filtering blood| EP2962104B1|2013-02-26|2018-04-04|Astute Medical, Inc.|Lateral flow assay device with test strip retainer| EP2994750B1|2013-05-07|2020-08-12|PerkinElmer Health Sciences, Inc.|Microfluidic devices and methods for performing serum separation and blood cross-matching| WO2015008991A1|2013-07-15|2015-01-22|주식회사 싸이토젠|Slide assembly| EP3617234A1|2013-08-07|2020-03-04|Astute Medical, Inc.|Assays for timp2 having improved performance in biological samples| EP3556863A1|2013-11-06|2019-10-23|Astute Medical, Inc.|Assays for igfbp7 having improved performance in biological samples| GB201403790D0|2014-03-04|2014-04-16|Ge Healthcare Ltd|Microfluidic devices and arrangements for introducing reagents and biological samples to such devices| EP2937890B1|2014-04-22|2020-06-03|Europlasma nv|Plasma coating apparatus with a plasma diffuser and method preventing discolouration of a substrate| US20150320347A1|2014-05-08|2015-11-12|Sedia Biosciences Corporation|Blood and biological sample collection device and method| US9986944B2|2014-05-08|2018-06-05|Sedia Biosciences Corporation|Blood and biological sample collection device and method| US10111610B2|2014-11-04|2018-10-30|Wainamics, Inc.|Microscale plasma separator| US10695702B2|2015-07-24|2020-06-30|Ahlstrom-Munksjö Oyj|Blood separation media and lateral flow devices for blood samples| WO2017040712A1|2015-09-01|2017-03-09|Polymer Technology Systems, Inc.|Systems and methods for blood sample preservation and hematocrit separation| JP6789107B2|2016-12-28|2020-11-25|富士フイルム株式会社|Blood test kit and blood analysis method| WO2018175169A1|2017-03-20|2018-09-27|Wainamics, Inc.|Small volume self-metered blood separation device| JP6542997B2|2017-03-30|2019-07-10|帝人株式会社|Blood cell separation membrane for immunochromatography and strip for immunochromatography| WO2021064276A1|2019-10-02|2021-04-08|Ahlstrom-Munksjö Oyj|Blood components collection and separation media, blood components collection and separation device comprising said media, and blood components separation and extraction process implementing said media| WO2021076846A1|2019-10-18|2021-04-22|Tasso, Inc.|Plasma separation devices and related methods| WO2021245025A1|2020-06-01|2021-12-09|Loop Diagnostics, S.L.|Method and kit for the early detection of sepsis|
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申请号 | 申请日 | 专利标题 DE3029579A|DE3029579C2|1980-08-05|1980-08-05|Method and means for separating plasma or serum from whole blood| 相关专利
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